sharepoint site is throwing AppDomainUnloadListener.RegisterSelf() entered lock(this=15368010) error in sharepoint logs

Hi,

i am unable to launch share point site as it is throwing below errors in share point logs

1.

AppDomainUnloadListener.RegisterSelf() entered lock(this=15368010)

2.

PublishingHttpModule.Init() calling AppDomainUnloadListener.Register()

at last, i am facing page cannot be displayed error.

please tell me how to resolve this error?

Thanks

Raju