Minimal Download Strategy is not compatible with Script of Demand because SOD is script and MDS load not load a content editor web part with script.
It is very common to load a script block /w SP.SOD.executeOrDelayUntilScriptLoaded
This ensures all artifacts are loaded before execution of JavaScript, and can be added on page using Content Editor Web Part, but this fails when /_layouts/15/start.aspx (MDS) attempts to load the page, but nothing will render (its script).
How to make Script On Demand and MDS work together?